Enoxolone Anti Inflammatory

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Pieces
Origin

China Mainland
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Description

Product Detail

Enoxolone Anti Inflammatory

Basic Info

· Product Name: Enoxolone anti-inflammatory

· Resource: 100% licorice roots

· Certificate: GMP

· Shelf Life:36 moths

· TOrigin: Shaanxi , China

· HS Code: 2938909030

· Trademark: FUJIE

· Specification: 10KG/carton

· Molecular formula:C30H46O4

· Molecular weight:470.7

· CAS NO:471-53-4

· Action and use: Cosmetics industry use in inflammatory

Enoxolone anti-inflammatory.png

structural formula

Solubility:Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.It shows polymorphism .

Specification:

Item	Specification
Assay	98.0-101.0%(dired substance)
Identification	Complies by TLC
Coloured reaction	Positive
Appearance	Fine Powder
Color	White or alomost
Melting point:	288-297?
Rotation :	+145° - +154°
Loss on Drying	=0.5%
Related Substance
Any impurity	=0.7%
Total impurity	=2.0%
Heavy metals	=10ppm
Sulphated Ash	=0.2%
Total Plate Count	NMT1000cfu/g
Total Yeast & Mold	NMT100cfu/g
E.Coli	Negative
Salmonella	Negative

Storage:

in sealed containers at cool & dry place.

Protect from light, moisture and pest infestation.

Anderso and Tillman was first noticed Enoxolone with hydrocortisone is similar in structure, it is used for the treatment of various skin diseases, by many clinical trials to confirm the effectiveness of Enoxolone anti-inflammatory. Therefore, a series of pharmacological studies have been carried out in the medical community, and many of these derivatives have anti-inflammatory activities. Zakirov's study found that 3- amino -11- deoxyglycyrrhizic acid showed clear anti - inflammatory activity in aseptic arthritis of all kinds of animals. Toyoshima et al. prepared 11- deoxidized glycyrrhizic acid maleate and its salt, as an anti - inflammatory agent, also as an anti-ulcer and immunomodulator, oral or local treatment, all achieved good curative effect.

Enoxolone has the anti - inflammatory effect of butadipine or hydrocortisone. Enoxolone has inhibitory effect on the granuloma of cotton granuloma of rats and the inflammation of the subcutaneous granulomatous inflammation, which is about 1/10 of cortisone or hydrogenation. The experimental arthritis in rats induced by glycyrrhizin was inhibited, and there was a different degree of inhibitory effect on the allergic reaction of guinea pigs. Its anti-inflammatory and antiallergic reactions may be associated with inhibition of capillary permeability, antihistamine, or decreased cell response to stimulation.

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