
Gliclazide CAS: 21187-98-4
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China Mainland
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Basic information of Gliclazide CAS: 21187-98-4
Name | Gliclazide |
Molecular Formula | C15H21N3O3S |
Molecular Weight | 323.41 |
QualityStandard | BP/EP |
Package Size | 25kg/drum |
Brief Introduction | Gliclazide is an oral hypoglycemic (anti-diabetic drug) and is classified as a sulfonylurea. Its classification has been ambiguous, as literature uses it as both a first-generation and second-generatio sulfonylurea. Gliclazide was shown to protect human pancreatic beta-cells from hyperglycemia-induced apoptosis. It was also shown to have an antiatherogenic effect (preventing accumulation of fat in arteries) in type 2 diabetes. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. |
Use of Gliclazide:
1)Anti-diabetic drug in treating diabetes.
COA ofGliclazide:
Tests | Specifications | Results |
Appearance | White or almost white powder | White powder |
Solubility | Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol (96%) | Meets the requirements |
Identifications | The infrared absorption spectrum is concordant with that obtained with gliclazide CRS | Meets the requirements |
Heavy metals | =10ppm | <10ppm |
Impurity B (HPLC) | =2ppm | 0.3ppm |
Related substance (HPLC) | Impurity F=0.1% Each unspecified impurity=0.10% Sum of impurities other than F=0.2% | N.D. 0.04% 0.1% |
Loss on drying | =0.25% | 0.02% |
Sulfated ash | =0.1% | 0.01% |
Assay(onanhydrousbasis) | 99.0%~101.0% | 99.7% |
Conclusion:Conforms with EP8 |
Ms. Penny Pan
International
Sales Department
Sinoway Industrial Co., Ltd
Add: 16/F.,
HUICHENG COMM. COMPLEX, 839 XIAHE RD., XIAMEN, P.R.CHINA
Tel:
0086-592-5881081
Fax:
0086-592-5854960
Skype: packey.pan
E-mail: pan@china-sinoway.com
Tax Registration No.:
9135020015498943XY
ISO
9001:2008, SGS Audited Supplier
Specializing in the research, development and custom manufacturing of gliclazide cas: 21187-98-4, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.
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