Gliclazide CAS: 21187-98-4

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Basic information of Gliclazide CAS: 21187-98-4

Name	Gliclazide
Molecular Formula	C15H21N3O3S
Molecular Weight	323.41
QualityStandard	BP/EP
Package Size	25kg/drum
Brief Introduction	Gliclazide is an oral hypoglycemic (anti-diabetic drug) and is classified as a sulfonylurea. Its classification has been ambiguous, as literature uses it as both a first-generation and second-generatio sulfonylurea. Gliclazide was shown to protect human pancreatic beta-cells from hyperglycemia-induced apoptosis. It was also shown to have an antiatherogenic effect (preventing accumulation of fat in arteries) in type 2 diabetes. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Use of Gliclazide:

1)Anti-diabetic drug in treating diabetes.

COA ofGliclazide:

Tests	Specifications	Results
Appearance	White or almost white powder	White powder
Solubility	Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol (96%)	Meets the requirements
Identifications	The infrared absorption spectrum is concordant with that obtained with gliclazide CRS	Meets the requirements
Heavy metals	=10ppm	<10ppm
Impurity B (HPLC)	=2ppm	0.3ppm
Related substance (HPLC)	Impurity F=0.1% Each unspecified impurity=0.10% Sum of impurities other than F=0.2%	N.D. 0.04% 0.1%
Loss on drying	=0.25%	0.02%
Sulfated ash	=0.1%	0.01%
Assay(onanhydrousbasis)	99.0%~101.0%	99.7%
Conclusion:Conforms with EP8

Ms. Penny Pan
International Sales Department
Sinoway Industrial Co., Ltd
Add: 16/F., HUICHENG COMM. COMPLEX, 839 XIAHE RD., XIAMEN, P.R.CHINA
Tel: 0086-592-5881081
Fax: 0086-592-5854960
Skype: packey.pan
E-mail: pan@china-sinoway.com

Tax Registration No.: 9135020015498943XY
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Specializing in the research, development and custom manufacturing of gliclazide cas: 21187-98-4, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.

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