Ademetionine 1,4-butanedisulfonate(SAM)

Product Name:Ademetionine 1,4-butanedisulfonate

CAS:101020-79-5

MF:2C15H23N6O5S.2C4H10O6S2.C4H8O6S2

MW:1451.63

Product Categories

Mol File:101020-79-5.mol

Item	Specification	Result	Test Method
Active Ingredeints
Assay(based on dried)	Succinic acid adenosine methionine95.0%~105.0%	98.40%	USP
Assay(based on dried)	Adenosine methionine cation50.0%~54.0%	51.80%	USP
Physical Control
Appearance	White or off-white power with Hygroscopic	Complies	Visual
Color	White	Complies	Visual
Identification	Positive	Complies	HPLC,UV,IR
Specific rotation[a]020	+14.9°+28°~+34°+17.3°	+31°	USP
Color of Solution	NMT Y2	Complies	USP
Clarity of Solution	NMT 1#	Complies	USP
Residue on ignition	0.1% Max(injection) 0.2%Max(oral)	0.08%	USP
Wet	3.0%Max	2.60%	USP
PH	1.8~2.5	2.3	USP
Chemical Control
Heavy metals	NMT10PPM	Conforms	CPh
Adenine	NMT0.5%	0.09%	CPh
S - adenosine - L homocysteine	NMT0.5%	0.05%	CPh
Aethylthioadenosine	NMT1%	0.23%	CPh
Succinic sulfonate(based on dried)	46.0%~49.0%	46.90%	CPh
(S) - S - adenosine methionine	60.0%~75.0%	71.20%	CPh
Impurity A	NMT2%	1.20%	CPh
Impurity B	NMT0.5%	0.04%	CPh
Other individual impurity	NMT0.1%	0.07%	CPh
Other total impurity	NMT1.0%	0.15%	CPh
Total impurity	NMT3.0%	1.80%	CPh
Endotoxin	=0.30 IU/mg	<0.02 IU/mg